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Even without medication, withdrawal symptoms and other problems subside over time

42 TOBACCOS SYNERGISTIC RISK FOR LUNG CANCER According to the National Cancer Institute (NCI), On average, current smokers have approximately 20 times the risk of lung cancer compared with nonsmokers. Tobacco smoking is estimated to cause 90% of lung cancer in males and 78% in females

Marketed as smoke-free substitutes for traditional cigarettes, theyre shaped like a long cigarette, battery operated, and filled with a replaceable cartridge of E-liquid that contains a mixture of ingredients such as nicotine, flavorings, glycerin and propylene glycol

Peer review Peer review information Nature Human Behaviour thanks Ram Bajpai and Olga Perski for their contribution to the peer review of this work