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For reasons science is still unraveling, smoking seems to interact with trauma-altered brain chemistry in ways that go beyond relief or habit. Nicotine or THC may balance or soothe these brains in ways people without PTSD or high ACE scores dont experience

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[132] [142] [143] Once FosB is sufficiently overexpressed, it induces an addictive state that becomes increasingly more severe with further increases in FosB expression