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Increased 12/15-lipoxygenase leads to widespread brain injury following global cerebral ischemia

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Vitamin C, or ascorbic acid, is essential for a variety of biological processes

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[22] Diphenhydramine acts as a reversible, competitive antagonist-and more precisely, an inverse agonist-at the histamine H receptor, thereby stabilizing the inactive receptor conformation and preventing histamine-mediated vasodilation, increased capillary permeability, and sensory nerve activation