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Effect on Transporter Protein Expression and Function For delivery via a transporter-mediated brain targeting approach, (pro)drugs and nanocarriers should possess high affinity to the transporter, which can affect the passage of physiologically important transporter substrates (210)

In addition, it is important to remember, that the ability to utilize the transporter does not guarantee a high extent of brain delivery, which should be evaluated in pharmacokinetic studies (79)

v.) verabreicht und provozierte eine Kardiomyopathie

Endogenous GLP-1 alters postprandial functional connectivity between homeostatic and reward-related brain regions involved in regulation of appetite in healthy lean males: A pilotstudy