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Recent advances have focused on three strategies: senolytics (eliminating senescent cells, e.g., dasatinib + quercetin), senomorphics (inhibiting the senescence-associated secretory phenotype, e.g., rapamycin), and senoreversion (rejuvenating senescent cells via epigenetic reprogramming)

Vitamin D reduces the inflammatory response by Porphyromonas gingivalis infection by modulating human -defensin-3 in human gingival epithelium and periodontal ligament cells

DNA binding protein e.g., HBGF-1 DNA can be delivered by bombardment of the skin by gold or other particles coated with DNA which are delivered by mechanical means, e.g., pressure

Consent for publication Not applicable (this is a review article)