ends tobacco products vs. smoking, how do they compare? Electronic nicotine delivery systems (ENDS):

These alterations contribute to systemic inflammation by increasing the production of pro-inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, IL-13, tumor necrosis factor-alpha (TNF-), and transforming growth factor-beta 1 (TGF-1) [24]

to refill, simply twist the mouthpiece off

A recent study from the University of Colorado Boulder found that cannabis use controlled key inflammatory agents and reduced peripheral inflammation (inflammation that occurs outside the central nervous system)

This can also cause circulation issues restricting blood flow to the scalp and a decreased delivery of vital nutrients and oxygen