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Other nicotine replacement products eliminate inhalation from the delivery which should work efficiently for reducing harm, however the success rates aren't as good when compared to vaping, so the question is: do E-Cigarettes count as harm reduction

This is also referred to as depolarization blockade

While some products offer a nicotine-free option, they should not be considered a risk-free alternative to smoking

However, vape aerosol still contains harmful and potentially dangerous chemicals other than nicotine like heavy metals, formaldehyde, and diacetyl, which is linked to a serious lung disease when inhaled (CDC, FDA)