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In reply, he forwarded samples of tumbeki of different growths and qualities

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The study of tobacco constituents has identified seminal knowledge of importance to our understanding of plant constituents (e.g., identification and structural elucidation of the ubiquitous plant constituent, solanesol), the first identification of the class known as cembranoids, the finding that novel sugar esters in the leaf waxes act as both insect repellent and as the aroma precursor for Oriental tobacco, the discovery of 2-acetylpyrazine with its characteristic "popcorn" aroma, and especially to our knowledge of carotenoid degradation which is of importance to the flavor and aroma of many flowers and foodstuffs