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However, caution is required in interpreting these results, as this perceivable benefit was accompanied with a significant elevation in liver enzymes, thus establishing these apparently beneficial changes as a mere reflection of the toxic damage of electronic cigarette liquid on the liver.94 Recently, electronic cigarettes have been proposed as a possible interfering factor in the splenocardiac axis, a signalling network involving the brain, autonomic nervous system and hematopoietic tissues

Both oxidized R-limonene and oxidized linalool have recently been patch tested in an international setting, showing contact allergy in 5.2% and 6.9% of dermatitis patients, respectively

by impaction or diffusion) 24 depends on the aerosol particle characteristics such as aerodynamic and mobility diameters, density, and volatility 25,26,27,28

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