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Response: Multiple studies have shown that people experienced very few to no withdrawal symptoms regardless of whether they reduced nicotine content immediately or tapered it off

Funding This study was supported by grants from the National Key R & D Program of China (2018YFC1705300) and the Research Program of Shanghai Sports Bureau (20Q001)

They also plan to evaluate larger populations exposed to longer periods of dermal THS

The research team divided the subjects into three groups to investigate the incidence of ulcerative colitis: 14,355,062 non-smokers (those who had never smoked or had smoked a total of five packs or less), 3,136,002 past smokers (those who had smoked five or more packs but had since quit), and 5,692,506 current smokers