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Grading of recommendations Recommendations are graded according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.21 Whether a recommendation is strong or conditional will depend on considerations such as certainty in estimated effects of an intervention, including magnitude, as well as estimates of how patients value and prioritize outcomes, variability of these estimates, and wise use of resources

Persons under 21 years of age may handle Restricted Products in the course of employment

You must be 21 or older to purchase, and an adult signature and/or ID check may be required at delivery depending on destination rules