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The researchers searched for the RCTs from a number of databases, including PubMed, EMBASE, Cochrane, and CINAHL

Upon stratifying the population based on age and severity of TR, there was no association between moderate-severe TR and 3-year mortality in patients pre-LTx and post-LTx with hazard ratios of 0.744 (95% CI 0.438-1.262) and 0.877 (95% CI 0.517-1.487) respectively

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