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Description

The present study demonstrated that NNMT inhibitor administered during adipocyte differentiation blocked the accumulation of lipid droplets, suggesting suppressed lipogenesis and programed development of mature adipocytes from pre-adipocyte 3T3-L1 precursor cells (i.e., adipogenesis)

5-Amino-1MQ also increases GLUT4 levels with similar results

Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment

It means that as a standalone oral therapy at the tested doses, it did not produce the magnitude of weight loss that pharmaceutical companies require for commercial viability