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Notably, PF has been observed to safeguard diabetic mice from myocardial ischemic injury by modulating the transient receptor potential vanilloid 1 (TRPV1)/calcitonin gene-related peptide signaling pathway ( FIGURE 4 3.7 Diabetic retinopathy (DR) DR often leads to vision impairment (Yue et al., 2022

149 Moreover, glycolysis may promote Treg proliferation via activation of the PI(3)KAktmTORC1 pathway and increase Treg migration via PI3KmTORC2-mediated glucokinase (GCK)actin binding