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Data to determine which billing units of discarded drugs are subject to discarded drug refunds generally will not be available until after CMS issues the Rebate Report to the manufacturer and none of the data available at the time of this report offer a reliable basis to estimate the amount of billing units that will be subject to discarded drug refunds

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Certain agents, notably ethambutol and linezolid, carry ocular toxicity risks such as optic neuropathy, while multidrug-resistant TB further limits effective options (Libershteyn, 2016)