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Serine metabolism, especially the de novo serine synthesis pathway, forms a metabolic network with glycolysis, folate cycle, and one-carbon metabolism, which is essential for rapidly proliferating cells

Materials and methods: EVs were isolated from patient plasma samples by ultracentrifugation in combination with SEC-based column purification

erinaceus has been studied as a potential therapeutic agent in inflammatory conditions involving the gut, such as inflammatory bowel disease (i.e ulcerative colitis (UC) and Crohns disease (CD))

One study elucidated a link between mutations in optineurin with pathology of primary open-angle glaucoma, emphasizing evidence of impaired mitophagy leading to the accumulation of damaged mitochondria (Shim et al., 2016)