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doi: 10.1002/ctm2.334 59

This accelerates skin aging over time and creates repeated opportunities for irritation and infection

Further, Ma et al

IDH1 and IDH2 isoforms are frequently mutated in various cancers, including glioma, acute myeloid leukemia, thyroid carcinomas, cartilaginous tumors, and intrahepatic cholangiocarcinoma (ICC) [66, 67, 68, 69]