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Decreased levels of H3K4me3 have also been identified at the upstream GAA repeat region, but not at the promoter region, which suggests a more pronounced defect of the post-initiation and elongation stages of FXN gene expression rather than an early transcription initiation defect (Punga and Buhler, 2010

[7] [15] References ^ a b c Michal G., Schomburg D

Mol Ther Nucleic Acids 16:407418 Zhang Y, Ouyang X, You S, Zou H, Shao X, Zhang G, Zhang C, Hu L (2020) Effect of human amniotic epithelial cells on ovarian function, fertility and ovarian reserve in primary ovarian insufficiency rats and analysis of underlying mechanisms by mRNA sequencing

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