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Nicotine and other stimulants in vaping products can activate the bodys fight or flight response and reduce heart rate variability, which may lead to irregular heart rhythms (arrhythmias) and, in severe cases, sudden cardiac arrest

Acetylcholine released by preganglionic sympathetic fibers of these nerves acts on nicotinic acetylcholine receptors, causing the release of epinephrine (and norepinephrine) into the bloodstream

Dealers in the illicit market may lace weed to stretch their product or increase potency, but this practice carries serious risks