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Ashton, K

The slow reaction between PfGrx C88S (S 2 ) and roGFP2 WT (SH) 2 was confirmed by electrophoretic mobility shift assays (Fig

65 A recently completed phase 3 trial in patients with clinically or genetically confirmed FCS with plozasiran, an siRNA inhibitor of APOC3 , demonstrated up to an 80% median reduction in triglycerides levels at month 10, as well as a statistically significant 83% reduction in the incidence of acute pancreatitis compared with placebo