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On July 24, 2026 the Committee will discuss three more

Light/UV Exposure Some amino acid residues are light-sensitive (e.g., tryptophan, tyrosine) and exposure to light/UV may degrade the peptide

Inevitably, even minor alterations in FcRn binding properties of a protein fusion can therefore affect the ability of the receptor to rescue it from intracellular lysosomal degradation