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Given the tobacco industrys history of duplicity, Alan Bluma of University of Alabama Center for the Study of Tobacco and Society might have summed it up the best in his 2008 review in the Lancet, stating, The search for a safer cigarette is akin to alchemists seeking to turn lead into gold. You might want to leave more room for squash

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O'Connor R, Watson CH, Swan GE, Nettles DS, Geisler RC, Hendershot TP (2020) PhenX: agent measures for tobacco regulatory research

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