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The half-life of singlet oxygen is ~ 4 s (Fujii et al

There are three classical signal transduction pathways involved in the development of endoplasmic reticulum stress: IRE1, PERK, and ATF6

The morphology and coreshell structure of nanoparticles was examined by transmission electron microscopy

30 , 31 Several preclinical studies have investigated the effect of high doses of vitamin C on challenging tumours such as glioblastoma multiform (GBM), breast cancer, colorectal cancer, mesothelioma and pancreatic cancer and showed promising results on the anticancer effect of vitamin C through hampering the tumour progression and tumour metastasis