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Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors Nature Communications New in the August 14, 2025, issue of NEJM: CagrilintideSemaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) CagrilintideSemaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial) cagrilintide fibrils GMP Cagrilintide 10mg The role of amylin, a gutbrain axis hormone, in metabolic and neurological disorders Muhammad 2025 FASEB BioAdvances Wiley Online Library

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Digestive Disorders Affecting the Small Intestine Conditions that damage or inflame the gut can reduce absorption, including: Celiac disease Crohns disease Small intestinal bacterial overgrowth (SIBO) Chronic infections (e.g., fish tapeworm) These conditions directly interfere with the ileum, where B12 is absorbed

doi:10.1056/NEJM199512213332507

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