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All cells were cultured in DMEM (HyClone, Cytiva, Marlborough, MA, USA) + 10% FBS (Gibco, Grand Island, NY, USA) and incubated at 37 C in a humidified atmosphere with 5% CO 2

Lorsque le glutathion hpatique est puis, les mtabolites ractifs de phase I s'accumulent et causent des lsions hpatocytaires

f , ABTS antioxidant assay (see Methods) for the proportion of ABTS radical quenched by supernatant isolated from the indicated strains after 72 h incubation in l-asparagine minimal medium (lacking l-DOPA)

The prediction of future conversion to MCI over 15 years is unlikely to be explained by undiagnosed cognitive impairment, placing changes detected by these aging models early in the causal chain of cognitive decline and neurodegenerative disease