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Hei 1-131,143) as an optical resolution reagent, resolving to obtain a desired form of the carnitine isomer in a suitable solvent by taking advantage of a solubility difference between the isomers, and then hydrolyzing the thus-resolved isomer to thereby obtain L-carnitine only

Regardless of the etiology, plasma concentrations of free carnitine 20 mol/L and increased acylcarnitine/free carnitine ratios (0.4) are considered abnormal (6)

Further, the process of the present invention provides advantages, such as environmental friendliness due to the use of an immobilized enzyme in the preparation of the intermediate, and applicability thereof to industrial-scale production arising from decreased production costs due to the recyclability of the enzyme

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