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Although it is contrary to cell death, pyroptosis can promote pulmonary vascular cell proliferation, induce vascular remodeling, and exacerbate PH

Gluud LL, Dam G, Les I, Marchesini G, Borre M, Aagaard NK, et al

Selmi C, Feghali-Bostwick CA, Lleo A, Lombardi SA, De Santis M, Cavaciocchi F, Zammataro L, Mitchell MM, Lasalle JM, Medsger T Jr, Gershwin ME (2012) X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma