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The first and last liver biopsies for each subject were selected for review

The femoral vein and then femoral artery were anastomosed

Gene expression profiling revealed pro-inflammatory responses in the liver of FBXL5 CD11c mice To investigate the mechanisms underlying the exacerbation of liver inflammation in APAP-treated FBXL5 CD11c mice, we performed RNA sequencing of whole liver of the control and FBXL5 CD11c mice with or without APAP treatment for 6 h