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First-in-human phase I trial of the PI3Kb-selective inhibitor SAR260301 in patients with advanced solid tumors (NCT01673737)

Deploying these nanoparticles ensures localized and controlled induction of ICD within the TIME, minimizing systemic toxicity while enhancing antitumor immunity [78,79,80]

The extracellular matrix (ECM) plays a crucial role in the process of tissue regeneration, participating in the proliferation, migration, and differentiation of various cells